End-to-end Service Provider of Spatial and Single-cell Multi-omics Technology
Discovery Genomics
Comprehensive Suite of NGS Services
Mirxes Genomics offers a wide range of Next-Generation Sequencing (NGS) services, delivering high-quality data with reliable turnaround time and cost-efficiency.
About Mirxes Genomics
Mirxes Genomics is a genomics and bioinformatics service provider that specializes in spatial and single-cell multi-omics technology, allowing comprehensive and detailed understanding of complex biological systems.
We are proud to be a Singapore-based service lab with ultra-high sequencing capacity – equipped with the only DNBSEQ-T10 Platform in APAC (outside of China).
Expert Bioinformatics Support
- Scalable and customizable workflows for analyzing large-scale omics data
- Public and private data harmonization and integrative analysis capabilities
Single-cell Whole Genome Sequencing
Single-cell Whole Genome Sequencing (scWGS) is a transformative technology that empowers the identification of somatic mutations present at remarkably low mosaicism levels, which is challenging for bulk sequencing. From uncovering developmental pathways to elucidating cancer progression, scWGS offers invaluable insights into the intricacies of biology and disease.
Mirxes Genomics offers the groundbreaking scWGS service utilizing Primary Template-directed Amplification (PTA), which addresses key challenges associated with Whole Genome Amplification (WGA) and demonstrates reduced error propagation. With expert experimental and bioinformatics support from Mirxes, researchers can readily harness scWGS to achieve extraordinary single-cell clarity.
scWGS Service Highlights
Detect Single-cell Mosaicism
Amplify trace amounts of genomic DNA from each single cell
Exceptional WGA Performance
High genome coverage and uniformity, low error and reduced artifacts
End-to-end Service
Available from sample preparation to bioinformatics analysis
Expert Bioinformatics Support
e.g. CNV, SNV and indel analysis at single-cell level
Unlock Single-cell Genomic Clarity
Partner with Us to Achieve Your Research Goals
Single-cell Whole Genome and RNA Sequencing
Experience the power of single-cell multi-omics, by performing Single-cell Whole Genome Sequencing (scWGS) and Single-cell RNA sequencing (scRNA-seq) on the same cell (scWGS+scRNAseq).
With Primary Template-directed Amplification (PTA) as the whole genome amplification (WGA) method, scWGS can be performed with reduced amplification artifacts, high genomic uniformity and low error propagation.
Mirxes Genomics offers scWGS+scRNAseq as an end-to-end service, supporting seamless integration of genomic variation data with transcriptional information to generate unparalleled insights into the drivers and consequences of cell heterogeneity.
scWGS+scRNAseq Service Highlights
Single-cell Multi-omics
Whole genome and mRNA transcriptome information obtained from the same cell
Exceptional WGA Performance
High genome coverage and uniformity, low error and reduced artifacts
Full Gene Body Coverage
Excellent detection of
full-length mRNA compared to 3’ scRNA-seq methods
Expert Bioinformatics Support
Bioinformatic heavy lifting of huge multi-omics datasets
Integrate Genomic and Transcriptomic Insights from the Same Cell
Partner with Us to Achieve Your Research Goals
Spatial Transcriptomics powered by Stereo-seq
Spatial Transcriptomics powered by Stereo-seq (SpaTial Enhanced REsolution Omics-sequencing) offers whole transcriptome profiling at nanoscale subcellular resolution, with a large field of view. It is a powerful research technology for spatial characterization of tumor microenvironment, construction of 3D transcriptomics models and spatiotemporal transcriptomics atlases in mammalian developmental biology, and many more applications.
Mirxes Genomics offers end-to-end service for Stereo-seq workflows, from tissue sectioning to bioinformatics tertiary analysis. Gene expression data is integrated with spatial information at a nanoscale resolution to generate unprecedented details.
Stereo-seq Service Highlights
Large Field of View
Chip sizes from 1cm x 1cm up to 2cm x 3cm available *depending on specific service
Single-cell Segmentation
Based on ssDNA-based algorithm or H&E staining on the same tissue section
Spatial Multi-omics Available
Stereo-seq FFPE (mRNA +
lncRNA + microbial RNA)
Experienced Service Provider
Successful work on extensive tissue types from various organisms since 2022
Spatial Transcriptomics
Fresh-Frozen Samples
Formalin-Fixed Paraffin-Embedded (FFPE) Samples
Partner with Us to Achieve Your Research Goals
Whole Genome Sequencing
Whole Genome Sequencing (WGS) enables comprehensive characterization of the entire human genome, including coding and non-coding regions.
Mirxes Genomics utilizes unique DNA nanoball sequencing (DNBSEQ) technology coupled with PCR-free library preparation to deliver results with high accuracy and low sequencing artifacts. Sequence alignment and variant calling are also available for our WGS services.
WGS Service Highlights
PCR-free Library
Minimize errors and amplification bias
High Sequencing Capacity
Up to 640 genomes in one run
High Quality Data
Q30 score of >80% for PE150 and >85% for PE100
Expert Bioinformatics Support
Custom analysis, with guaranteed data security
Maximize Research Output with Affordable Sequencing
Partner with Us to Achieve Your Research Goals
Whole Exome Sequencing
Whole exome sequencing (WES) is a widely used genomic technique targeting protein-coding regions of the genome, presenting as a cost-efficient alternative to WGS that allows increased coverage of regions of interest.
Mirxes Genomics offers the options to focus on coding sequences with guaranteed >99% coverage, or to customize panels for comprehensive capture of coding sequences for discovery. Additional spike-ins are available, for example of genes relevant to various diseases and cancers, as well as 100% of the mitochondrial genome. Variant calling based on best practices is available with every WES service.
WES Service Highlights
Twist NGS ProLab
Certified NGS provider by Twist Bioscience
Flexible Exome Targeting
Easily customizable spike-in content into the exome panel
High Quality Data
Q30 score of >85% for PE150 and PE100
Expert Bioinformatics Support
Custom analysis, with guaranteed data security
Maximize Research Output with Affordable Sequencing
Partner with Us to Achieve Your Research Goals
Methylation Sequencing
DNA methylation is a type of heritable epigenetic modification which regulates gene expression without altering the DNA sequence. DNA methylation landscapes have been known to be associated with development, ageing and complex diseases including various cancers and neurological disorders.
To investigate DNA methylation patterns, researcher may adopt a whole genome approach or a targeted approach. Whole Genome Methylation Sequencing (WGMS) offers the ability to interrogate genome-wide DNA methylation patterns at single base resolution. Meanwhile, targeted methylation sequencing allows for higher sequencing depth and coverage of enriched genomic regions of interest.
Mirxes Genomics provides both WGMS and targeted methylation sequencing as end-to-end services, enabling high-throughput methylation analysis and robust bioinformatics support for analysis of large datasets.
Methylation Sequencing Service Highlights
Enzymatic Methyl Sequencing
Minimize DNA damage and ensure uniform GC coverage
Deep Sequencing Available
≥ 100x coverage available
High Quality Data
Q30 score of >80% for PE150 and PE100
Expert Bioinformatics Support
Support for large datasets, with guaranteed data security
Investigate Methylation Patterns
Whole Genome Methylation
Targeted Methylation
Shotgun Metagenomic Sequencing
Shotgun Metagenomic Sequencing involves untargeted sequencing of all microbial genomes in each sample, enabling unbiased characterization and in-depth study of microbial communities in their living environments. Discover the diversity and functional potential of microbiome, which plays a major role in human health and disease.
Mirxes Genomics offers high throughput Shotgun Metagenomic Sequencing, complete with Bioinformatics analysis customized to meet your specific project requirements.
Shotgun Metagenomic Sequencing Service Highlights
Study Host-Microbiome Interactions
Both host and microbial genomes are sequenced and available for analysis
Expert Bioinformatics Support
Custom analysis, with guaranteed data security
PCR-free Library
Minimize errors and amplification bias
High Sequencing Throughput
High-capacity sequencers to generate more data for insightful analysis
Discover the Diversity and Functional Potential of Microbiome
Partner with Us to Achieve Your Research Goals
RNA Sequencing
RNA Sequencing (RNA-Seq) is an indispensable tool for transcriptome-wide analysis of differential gene expression and structural analysis of RNAs.
Mirxes Genomics offers an efficient package for stranded RNA-Seq, with rRNA depletion and the synthesis of cDNA libraries from a wide input range of total RNA, allowing for profiling of coding and non-coding RNA while retaining knowledge of transcript orientation. These libraries are then sequenced using DNBSEQ technology, generating high quality data for comprehensive analysis of gene expression, as well as discovery of alternate splicing events, gene fusions and other transcriptomic variations.
RNA-Seq Service Highlights
Stranded RNA-Seq
Allow determination of transcript orientation
rRNA Depletion
Profile both coding and non-coding RNA
High Quality Data
Q30 score of >85% for PE150 and PE100
Expert Bioinformatics Support
Custom analysis, with guaranteed data security
Maximize Research Output with Affordable Sequencing
Partner with Us to Achieve Your Research Goals
Pre-made Library Sequencing
Mirxes Genomics provides standalone sequencing service to researchers preparing their own libraries. We work with strict quality controls and optimized sequencing workflows to deliver high-quality data for your research. We accept various types of pre-made libraries for sequencing on high-throughput DNBSEQ-T7 and T10 platforms.
Experience in sequencing a wide variety of libraries:
Illumina
- TruSeq DNA
- TruSeq RNA
New England Biolabs
- NEBNext
10x Genomics
- Chromium Single Cell Gene Expression Flex
- Chromium Next GEM Single Cell 3ʹ
- Chromium Next GEM Single Cell 5’
- Chromium Single Cell 3′ with Feature Barcoding
- Chromium Next GEM Single Cell ATAC
- Visium Spatial Gene Expression
Olink
- Olink Explore
Mission Bio
- Tapestri
MGI Tech
- MGI DNBelab C4
Dovetail
- Micro-C
We are able to convert most Illumina-compatible libraries for DNBSEQ sequencing.
Do contact us if you would like to explore libraries beyond what is listed above.
Pre-made Library Sequencing Service Highlights
High Quality Data
Q30 score of >85% for PE150 and PE100
Cost Efficiency
Revolutionizing the cost of sequencing with ultra-high throughput
Obtain Quality Sequencing Data with Cost Savings
10x Genomics scRNA-seq Libraries
All Other Library Types
Mirxes Bioinformatics
Data is at the heart of biotechnology research and pharmaceutical innovation. Mirxes Genomics has the specialized bioinformatics expertise, experience and infrastructure to unlock the valuable insights in your single-omics or multi-omics data.
Design, Develop and Deliver
We recognize that every research project is unique and has its own distinct objectives, requirements and challenges. A dedicated team of experts from Mirxes Genomics will work with you, to understand your research question and design a customized analysis solution. With proactive discussions, intuitive visualizations, and publication-ready methodology, we provide personalized and dedicated support at each stage of your study.
Grant Application Support
Pre-Project Consultation
Regular Data Review Meetings
Generation of Publication-Ready Figures
Mirxes Genomics is your reliable co-development partner, committed to offering tailored support to complement your existing resources, starting from the inception of a project to culmination in a successful publication.
Our Omics Data Processing Experience
210 TB
Spatial Data
350 TB
Single Cell Data
(Updated Feb 2025)
Key Service Highlights
Scalable
Compute Power
to Perform Variant Calls Using >=800X Depth of Coverage WGS Data
Spatially
Aware Analysis
to Study Functional Domains and Cellular Neighborhoods
Spatial
Metatranscriptomics
to Resolve Host-Microbial Interactions in Tissue Microenvironment
Speak to our Bioinformatics Experts
Contact Us
Our Locations
Genomics Lab Facility
8 Biomedical Grove
#02-01/04 Neuros
Singapore 138665
MM-008-W_r00
SOCIAL MEDIA
- Genomics
- Clinical Sequencing
- Discovery Genomics
- Cancer Screening
- GASTROClear for Patients
- GASTROClear for Medical Professionals
- LUNGClear
- Cancer Treatment Selection
- APEX Tissue
- COMPASS Tissue
- Infectious Diseases
- Fortitude 2.1
- Fortitude 3.0
- Fortitude Syndromic Panel
- CoVClear Mutation Panel
- Swab & Saliva Collection
- RNA Extraction Kit & Instruments